Genetic Risk analysis for Melanoma Skin Cancer for Men and Women

The Better2Know Genetic Melanoma Cancer Risk analysis for men and women will reveal your unique genetic risk for developing a Melanoma Skin Cancer during your lifetime. You will receive tailored medical recommendations designed to empower you with effective strategies for prevention and early detection. This analysis uses polygenic risk scoring (PRS) based on hundreds of common genetic variants, giving you the most reliable indicators of melanoma skin cancer risk available.

The Better2Know Personalised Genetic Melanoma Skin Cancer Risk analysis for men and women will assess your risk for:

• Melanoma Skin Cancer

What cancer that this test will assess?

Melanoma skin cancer occurs when certain cells in your skin start to grow and divide in an abnormal way. It starts in cells called melanocytes, which are the skin cells involved in the production of melanin, the pigment or colouring that makes you look tanned or brown skinned. This pigment helps to protect your body against ultraviolet light (UV radiation) from the sun, but sun beds and tanning booths can also deliver this type of radiation.

UV radiation can cause sunburn. Sunburn is directly involved in damage to the DNA (the genetic material in your cells) of your skin cells and this DNA damage can directly lead to Melanoma Skin Cancer.

What kinds of Skin Cancer are there?

There are two main types of Skin Cancer. The first is non-melanoma skin cancer. This Skin Cancer can include basal cell skin cancer, squamous cell skin cancer and a few other rare types of skin cancer.

The second type of skin cancer is Melanoma skin cancer. Melanoma skin cancer can start anywhere on the skin, including in a mole, as a new blemish on a patch of previously clear skin, on the palms of your hands or the soles of your feet. It can sometimes start under your fingernails, and appear as a dark streak running up under your nails.

How common is Melanoma Skin Cancer?

Every year, over 17,500 people across Great Britain are diagnosed with Melanoma Skin Cancer. Unfortunately, the rates of diagnosis are increasing so it is very important that you assess your risk of developing a Melanoma Skin cancer and get any worrying spot or blemish looked at by a doctor as soon as possible. Melanoma Skin Cancer is the 5th most common type of cancer in the UK.

Who is at risk of Melanoma Skin Cancer?

People with fair or pale skin, red hair or freckles are generally more prone to developing melanoma skin cancer. People with darker complexions are less likely to develop melanoma skin cancer but are not immune to it. Melanoma Skin Cancer can develop at any age but it is more common in older people. The main cause of Melanoma skin cancer is exposure to UV radiation from the sun or tanning beds and salons. Other risk factors include your hair and eye colour, with blue or green eyes putting you at greater risk, the number of moles you have on your body, and any family history of Melanoma Skin Cancer

Why should I choose personalised prevention?

Every person is different and each of us has our own unique risk profile for developing certain diseases and cancers. This polygenic risk test will determine your personal genetic risk of developing Melanoma skin cancer. Inherited genetic mutations are the cause of 5–10% of Melanoma Skin cancer cases in men and women. Finding out that you have a mutation that increases your risk, enables you and your healthcare provider to develop a personalised plan designed to prevent or detect cancer at an earlier stage.

• Discover your genetic risk level for Melanoma skin cancer.
• Powered by clinical-grade, MHRA registered, CE-marked genetic testing from a saliva sample collected at home
• Get personalised guidance on when to start Melanoma skin cancer screening and how often
• Learn actionable steps to reduce your risk
• Recommended for men and women aged 18 and above, or anyone who visits tanning salons or is exposed to high levels of UV radiation

Take the first step – order your personalised prevention plan today!

The Reality of Melanoma Skin Cancer for Men and Women

• Melanoma skin cancer deaths in the UK have increased by over 140% in the past 50 years.
• Up to 90% of Melanoma skin cancers are preventable with early detection and measures.

We Can Change This – With Personalised Prevention!

Next-Generation Prevention: Tailored to Your Unique Genetic Profile

Personalised Melanoma skin cancer prevention with genetic risk assessment provides early warnings, even in individuals with no family history of cancer. Our tests guide you toward tailored screening and prevention strategies based on your unique risk level.

What is a Polygenic Risk Score?

The Polygenic Risk Score (PRS) measures disease risk based on the analysis of hundreds of genetic variants. Our PRS technology calculates the combined effect of these variants to determine your personalised risk score for developing Melanoma skin cancer.

• Many cancers result from a combination of multiple genetic factors, making them polygenic.
• Even without a family history of cancer, your polygenic risk may still be significant.
• Incorporating PRS with your background (age, sex, ethnicity), we provide accurate risk assessments and tailored medical advice.

Who should take this test?

• Men and Women aged 18 and above, regardless of family history
• Those who want to be proactive about their health
• Anyone seeking personalised medical prevention strategies

What is the Better2Know Personalised Melanoma Skin Cancer Prevention Plan for Men and Women testing process?

Follow these three simple steps to your personalised Melanoma skin cancer prevention plan

• Order your test kit today and have it delivered directly to your home.
• Provide a saliva sample using the simple saliva collection kit and return it using the enclosed prepaid envelope.
• Receive your personalised report online within six to eight weeks, complete with clear guidance on your next steps. Each report includes your polygenic risk level, screening recommendations, and lifestyle guidance.

Certified and Trusted Testing with Better2Know

Our tests are fully compliant with all regulatory bodies and are government-approved

• CE-marked medical devices (in vitro diagnostics, IVD)
• Registered in the UK MHRA Registry and EUDAMED database
• Developed using anonymised data from the UK Biobank ensuring high accuracy and applicability

Comprehensive Insights on your genetic risks await you:

• What is your genetic risk level for Melanoma skin cancer?
• When should you start screening, and how often?
• Are there additional measures you can take to lower your risk?
• What steps can you take to reduce your likelihood of developing Melanoma cancer?
• What changes or symptoms should you monitor?
• What should your doctor know?

When will my home testing kit arrive?

If you order before 4pm, Monday to Friday, we can send your Melanoma skin cancer panel test on the very same day, by sending your test by First Class Royal Mail.

How will I receive my test results?

You will receive your comprehensive results report around 6 – 8 weeks once our lab has received your sample.

What should I do with my results?

If your test shows that you are at increased risk of developing Melanoma skin cancer, optional genetic counselling can be provided for those identified as being at elevated risk.

How can I order my home test?

You can order your personalised Melanoma skin cancer prevention plan for men and women by adding the test to your basket and proceeding to payment. You can also call Better2Know on the number displayed at the top of the page. Our team of expert advisors will be able to help you process your order and answer any additional questions you may have. For your convenience, our lines are open 24/7.

Frequently Asked Questions

• How long is my saliva sample stable for during transit? Saliva samples remain stable for up to 6 months under suitable conditions.
• When will I receive my test results? Once your sample is received at the laboratory, results are typically reported within six to eight weeks. If you haven’t received your results after this time, please contact us.
• How will I get my results? Your comprehensive report will be sent to you within 6 to 8 weeks of our laboratory receiving your sample. The notification about your results will be sent to the email address you provided. If needed, our medical team will contact you to arrange a convenient time to discuss your results.
• Does this test analyse rare mutations in genes that increase cancer risk? No, this Melanoma skin cancer test does not assess rare pathogenic mutations in genes which can significantly increase the risk of developing Melanoma skin cancer.
• Is this test used to diagnose cancer? No, this test is designed to assess your genetic predisposition and provide personalised prevention strategies, not diagnose cancer.
• Does an elevated risk mean I will develop cancer? No, an elevated risk does not guarantee you will develop cancer. Similarly, a moderate or lower risk does not mean your risk is zero.
• Does this test assess the risk for my family members? No, the test evaluates your personal risk. Polygenic risk scores are not directly inherited in a way that can predict risks for relatives.
• What else should I consider alongside my test results? Your test results should be interpreted alongside other clinical data. Lifestyle, diet, and other health factors also play a role in cancer risk.